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Tg(IGH-GPR183)1Rosm
Transgene Detail
Summary
Symbol: Tg(IGH-GPR183)1Rosm
Name: transgene insertion 1, Mette Rosenkilde
MGI ID: MGI:6148065
Synonyms: IgH-hEBI2
Transgene: Tg(IGH-GPR183)1Rosm  Location: unknown  
Alliance: Tg(IGH-GPR183)1Rosm page
Transgene
origin
Strain of Origin:  CBA
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(IGH-GPR183)1Rosm expresses 1 gene
 
Mutation detailsThe human GPR183 (EBI2) gene is expressed under the control of an intronic IgH enhancer/promoter. Expresssion is primarily in CD19+ B cells and thus is most abundant in the spleen. (J:240111)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:240111 Niss Arfelt K, et al., EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies. Blood. 2017 Feb 16;129(7):866-878
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory