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Tg(GFAP-GCaMP3)1Kdmc
Transgene Detail
Summary
Symbol: Tg(GFAP-GCaMP3)1Kdmc
Name: transgene insertion 1, Kevin D McCarthy
MGI ID: MGI:6148047
Synonyms: Gfap-GCaMP3
Transgene: Tg(GFAP-GCaMP3)1Kdmc  Location: unknown  
Alliance: Tg(GFAP-GCaMP3)1Kdmc page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe human GFAP promoter drives expression of this transgene that includes a mutagenized green fluorescent calcium indicator (GCaMP3), woodchuck hepatitis virus posttranscriptional regulatory element (WPRE), and SV40 polyadenylation sequence. GCaMP consists of a circularly permutated green fluorescent protein (cpGFP), the calcium-binding protein calmodulin (CaM), and CaM-interacting M13 peptide. (J:258504)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:258504 Xie AX, et al., Ganglionic GFAP (+) glial Gq-GPCR signaling enhances heart functions in vivo. JCI Insight. 2017 Jan 26;2(2):e90565
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory