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Tg(Col1a1-Dspp*D452A)4Cqi
Transgene Detail
Summary
Symbol: Tg(Col1a1-Dspp*D452A)4Cqi
Name: trasngene insertion 4, Chunlin Qin
MGI ID: MGI:6148032
Synonyms: D452A-DSPP transgene
Transgene: Tg(Col1a1-Dspp*D452A)4Cqi  Location: unknown  
Alliance: Tg(Col1a1-Dspp*D452A)4Cqi page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Col1a1-Dspp*D452A)4Cqi expresses 1 gene
 
Mutation detailsExpression of a cDNA encoding a mutant DSPP in which Asp-452 was substituted by Ala-452 is driven by a rat Col1a1 promoter. (J:248707)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:248707 Zhu Q, et al., Partial blocking of mouse DSPP processing by substitution of Gly(451)-Asp(452) bond suggests the presence of secondary cleavage site(s). Connect Tissue Res. 2012;53(4):307-12
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory