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Gene Expression Data
Assay Details
Assay
Reference: J:95019 Manley NR, et al., Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol. 2004 Dec 15;276(2):301-12
Assay type: RNA in situ
MGI Accession ID: MGI:6148022
Gene symbol: Tbx1
Gene name: T-box 1
Probe: Tbx1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme Present 6I
TS15: 2nd branchial arch mesenchyme Present 6I
TS15: otocyst Present Regionally restricted 6I Expression in posterior half of otic vesicle.
TS15: 3rd branchial pouch endoderm Present 6I
Specimen 6J: embryonic day 9.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme Present 6J
TS15: 2nd branchial arch mesenchyme Present 6J
TS15: otocyst Present 6J
TS15: 3rd branchial pouch Present Regionally restricted 6J Loss of expression in region where third pouch should form.
Specimen 6K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 3rd branchial pouch endoderm Present Regionally restricted 6K Expression in third pouch restricted to specific anterior-dorsal domain.
Specimen 6L: embryonic day 10.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS17: 3rd branchial pouch Present Diffuse 6L Diffuse expression throughout the third pouch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory