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Gene Expression Data
Assay Details
Assay
Reference: J:95019 Manley NR, et al., Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol. 2004 Dec 15;276(2):301-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6148017
Gene symbol: Pbx1
Gene name: pre B cell leukemia homeobox 1
Antibody: anti-Pbx1b
Results
Specimen 4A,B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS16: 4th branchial arch ectoderm Present Regionally restricted 4A , 4B Nuclearly localized expression most prominent in mesenchyme, endoderm and ectoderm of the fourth arch.
TS16: 4th branchial arch mesenchyme Present Regionally restricted 4A , 4B Nuclearly localized expression most prominent in mesenchyme, endoderm and ectoderm of the fourth arch.
TS16: 4th branchial pouch endoderm Present Regionally restricted 4A , 4B Nuclearly localized expression most prominent in mesenchyme, endoderm and ectoderm of the fourth arch.
TS16: branchial arch Present Graded 4B , 4A Authors report graded expression anterior to 4th branchial arch region.

Specimen 4C,D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch ectoderm Strong Regionally restricted 4C , 4D Highest levels of nuclear expression in surface ectoderm and pouch endoderm throughout the pharyngeal region.
TS17: branchial pouch endoderm Strong Regionally restricted 4C , 4D Highest levels of nuclear expression in surface ectoderm and pouch endoderm throughout the pharyngeal region.
TS17: 3rd branchial arch mesenchyme Present Regionally restricted 4C , 4D Mesenchymal localization of expression more prominent in subsets of mesenchyme in arches three and four. Expression least prominent in mesenchyme surrounding the third pouch in region where thyroid/parathyroid primordia form.
TS17: 4th branchial arch mesenchyme Present Regionally restricted 4C , 4D Mesenchymal localization of expression more prominent in subsets of mesenchyme in arches three and four. Expression least prominent in mesenchyme surrounding the third pouch in region where thyroid/parathyroid primordia form.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory