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Gene Expression Data
Assay Details
Assay
Reference: J:92327 Adamska M, et al., En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol. 2004 Aug 1;272(1):134-44
Assay type: RNA in situ
MGI Accession ID: MGI:6147812
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA13
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A wildtype: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 3A wildtype
Specimen 3A En1-/-: embryonic day 10.5; En1tm1Alj/En1tm1Alj (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 3A En1-/- Authors report expression in expanded apical ectodermal rige.
TS17: forelimb bud ectoderm Present Regionally restricted 3A En1-/- Expression encompases half of ventral forelimb ectoderm.
Specimen 4A Fgf8: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 4A Fgf8 distal , 4A Fgf8 ventral
Specimen 4B Fgf8: embryonic day 11.5; Wnt7atm1Amc/Wnt7atm1Amc (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 4B Fgf8 distal , 4B Fgf8 ventral
Specimen 6A forelimb: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 6A forelimb
Specimen 6A hindlimb: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 6A hindlimb
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory