Tg(Lrrc6/Venus)12Hmd
Transgene Detail
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| Symbol: |
Tg(Lrrc6/Venus)12Hmd |
| Name: |
transgene insertion 12, Hiroshi Hamada |
| MGI ID: |
MGI:6147718 |
| Synonyms: |
Lrrc6::Venus |
| Transgene: |
Tg(Lrrc6/Venus)12Hmd Location: unknown
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| Alliance: |
Tg(Lrrc6/Venus)12Hmd page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The Venus reporter was inserted in-frame before the stop codon in BAC clone RP24-333G17. A fully functional fusion protein expressed from this construct was capable of rescuing the Lrrc6 null lethal phenotype. The Lrrc6::Venus protein was localized in the cytoplasm of E8.0 node cells but not in the axoneme of node cilia. Similarly, the fusion protein was localized only in the cytoplasm of tracheal epithelial cells and primary spermatocytes and spermatids in the testis.
(J:258369)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:258369 Inaba Y, et al., Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6. Genes Cells. 2016 Jul;21(7):728-39 |
| All: |
1 reference(s) |
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Analysis Tools
