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Gene Expression Data
Assay Details
Assay
Reference: J:21884 Stark K, et al., Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994 Dec 15;372(6507):679-83
Assay type: RNA in situ
MGI Accession ID: MGI:6144253
Gene symbol: Wnt4
Gene name: wingless-type MMTV integration site family, member 4
Probe: Wnt4 cDNA12
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1a: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present Regionally restricted 1a Expressed in condensed mesenchymal cells on both sides of the stalk of the ureter, correlated to the site where the first pretubular cell aggregates form.
Specimen 1b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present Regionally restricted 1b Expressed in condensed mesenchymal cells on both sides of the stalk of the ureter, correlated to the site where the first pretubular cell aggregates form.
Specimen 1c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pretubular aggregate Present 1c
TS20: mesenchyme of metanephros Present Regionally restricted 1c Expressed in area adjacent to the mesonephric duct.
Specimen 1d: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pretubular aggregate Present 1d primitive tubular aggregates
Specimen 1e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pretubular aggregate Present 1e
TS22: comma-shaped body Present 1e
TS22: s-shaped body Present Regionally restricted 1e Expressed transiently to the region where epithelial fusion was occurring with the collecting duct.
Specimen 1f: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: pretubular aggregate Present 1f
Specimen 4m: embryonic day 12.5 (more )
Note: It is not specified the sample is from wild-type or the heterozygous.
Structure Level Pattern Image Note
TS20: pretubular aggregate Present 4m
Specimen 4n: embryonic day 12.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present 4n
TS20: primitive collecting duct Absent 4n
Specimen 4o: embryonic day 14.5 (more )
Note: It is not specified the sample is from wild-type or the heterozygous.
Structure Level Pattern Image Note
TS22: comma-shaped body Present 4o
TS22: pretubular aggregate Present 4o
TS22: s-shaped body Present 4o
TS22: collecting duct Present 4o
Specimen 4p: embryonic day 14.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Level Pattern Image Note
TS22: metanephros Trace Regionally restricted 4p Occasional expression in poorly developed aggregates.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory