Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ugt1tm2Rhtu
Name:	UDP glucuronosyltransferase 1 complex; targeted mutation 2, Robert Tukey
MGI ID:	MGI:6144034
Synonyms:	Ugt1F
Gene:	Ugt1  Location: unknown  Genetic Position: Chr1, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:202977
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The targeting vector contains an unspecified selection cassette that was used to insert a loxP site into intron 2, and another loxP site into intron 4. (J:202977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ugt1 Mutation:	2 strains or lines available

Original:	J:202977 Chen S, et al., Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19143-8
All:	1 reference(s)