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Gene Expression Data
Assay Details
Assay
Reference: J:210988 Kawasaki M, et al., R-spondins/Lgrs expression in tooth development. Dev Dyn. 2014 Jun;243(6):844-51
Assay type: RNA in situ
MGI Accession ID: MGI:6144021
Gene symbol: Rspo4
Gene name: R-spondin 4
Probe: R-spondin4 probe1
Probe preparation: labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1P: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: oral region Absent 1P No expression in presumptive molar tooth region.

Specimen 1Q: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: jaw primordium Absent 1Q No expression in presumptive molar region.

Specimen 1R: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: molar epithelium Weak Regionally restricted 1R Weak expression in basal epithelium of tooth bud.
TS21: molar mesenchyme Weak 1R

Specimen 1S: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: molar dental papilla Present 1S
TS22: cervical loop Weak Regionally restricted 1S Weak expression in cervical loop epithelium.

Specimen 1T: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: molar dental papilla Present Regionally restricted 1T Strong expression in developing pulp. Weak expression in odontoblasts.
TS26: molar enamel organ Weak Regionally restricted 1T Weak expression in ameloblasts.

Specimen 3C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cervical loop Present Regionally restricted 3C Expression in lingual aspect of cervical loop.
TS26: incisor dental papilla Present Regionally restricted 3C Expression in lingual side of developing dental pulp.
TS26: incisor mesenchyme Weak Regionally restricted 3C Weak expression in mesenchyme facing the cervical loop.

Specimen 8C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: jaw Present Regionally restricted 8C Expression in diastema (tooth less region) anterior to first molar tooth germs.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory