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Gene Expression Data
Assay Details
Assay
Reference: J:235223 Omori H, et al., Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016 Aug;590(16):2584-93
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6120547
Gene symbol: C2cd4c
Gene name: C2 calcium-dependent domain containing 4C
Reporter: lacZ
Direct Detection
Results
Specimen 3B left: embryonic day 18.5; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; magenta - Ins1 (assay MGI:6120548) and Ins2 (assay MGI:6120549).
Structure Level Pattern Image Note
TS26: endocrine pancreas Present 3B SPiDER-beta-gal/Ins Many positively stained cells overlapped with Insulin-positive cells.
Specimen 3B left center: embryonic day 18.5; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; red - Gcg (assay MGI:6120546).
Structure Level Pattern Image Note
TS26: endocrine pancreas Present 3B SPiDER-beta-gal/Gcg Few of the positively stained cells overlapped with Glucagon-positive cells.
Specimen 3B right center: embryonic day 18.5; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; red - Sst (assay MGI:6120552).
Structure Level Pattern Image Note
TS26: endocrine pancreas Present 3B SPiDER-beta-gal/Sst Few of the positively stained cells overlapped with Sst-positive cells.
Specimen 3B right: embryonic day 18.5; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; red - Ppy (assay MGI:6120550).
Structure Level Pattern Image Note
TS26: endocrine pancreas Present 3B SPiDER-beta-gal/PP Many positively stained cells overlapped with Ppy-positive cells.
Specimen 3C bottom left: postnatal adult; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; magenta - Ins1 (assay MGI:6120548) and Ins2 (assay MGI:6120549).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 3C SPiDER-beta-gal/Ins Staining overlapped with Insulin-positive beta cells in the islets.
Specimen 3C bottom left center: postnatal adult; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; red - Gcg (assay MGI:6120546).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 3C SPiDER-beta-gal/Gcg Staining was noted in islets and did not overlap with Gcg.
Specimen 3C bottom right center: postnatal adult; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; red - Sst (assay MGI:6120552).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 3C SPiDER-beta-gal/SS Staining was noted in islets and did not overlap with Sst.
Specimen 3C bottom right: postnatal adult; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: green - C2cd4c; red - Ppy (assay MGI:6120550).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 3C SPiDER-beta-gal/PP Staining was noted in islets and did not overlap with Ppy.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory