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Gene Expression Data
Assay Details
Assay
Reference: J:235223 Omori H, et al., Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016 Aug;590(16):2584-93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6120546
Gene symbol: Gcg
Gene name: glucagon
Results
Specimen 3B: embryonic day 18.5; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: red - Gcg; green - C2cd4c (assay MGI:6120547).
Structure Level Pattern Image Note
TS26: endocrine pancreas Present 3B SPiDER-beta-gal/Gcg Few immunopositive cells overlapped with C2cd4c SPiDER-beta-gal stained cells.
Specimen 3C bottom: postnatal adult; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: red - Gcg; green - C2cd4c (assay MGI:6120547).
Structure Level Pattern Image Note
TS28: endocrine pancreas Present 3C SPiDER-beta-gal/Gcg Immunostaining did not overlap with C2cd4c.
Specimen 5B C2cd4c+/+: embryonic day 14.5 (more )
Note: Double labeled: red - Gcg; green - Ins1 (assay MGI:6120556) and Ins2 (assay MGI:6120557).
Structure Level Pattern Image Note
TS22: pancreas epithelium Present 5B C2cd4C+/+ Merge , 5B C2cd4C+/+ Gcg Expression was detected in alpha cells.
Specimen 5B C2cd4c+/-: embryonic day 14.5; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: red - Gcg; green - Ins1 (assay MGI:6120556) and Ins2 (assay MGI:6120557).
Structure Level Pattern Image Note
TS22: pancreas epithelium Present 5B C2cd4C+/- Gcg , 5B C2cd4C+/- Merge Expression was detected in alpha cells normally.
Specimen 5B C2cd4c-/-: embryonic day 14.5; C2cd4ctm1(KOMP)Mbp/C2cd4ctm1(KOMP)Mbp (more )
Note: Double labeled: red - Gcg; green - Ins1 (assay MGI:6120556) and Ins2 (assay MGI:6120557).
Structure Level Pattern Image Note
TS22: pancreas epithelium Present 5B C2cd4C-/- Merge , 5B C2cd4C-/- Gcg Expression was detected in alpha cells normally.
Specimen 6B C2cd4c+/+: postnatal adult (more )
Note: Double labeled: red - Gcg; green - Ins1 (assay MGI:6120556) and Ins2 (assay MGI:6120557).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 6B C2cd4C+/+ Gcg , 6B C2cd4C+/+ Merge
Specimen 6B C2cd4c+/-: postnatal adult; C2cd4ctm1(KOMP)Mbp/C2cd4c+ (more )
Note: Double labeled: red - Gcg; green - Ins1 (assay MGI:6120556) and Ins2 (assay MGI:6120557).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 6B C2cd4C+/- Merge , 6B C2cd4C+/- Gcg Normal expression was detected.
Specimen 6B C2cd4c-/-: postnatal adult; C2cd4ctm1(KOMP)Mbp/C2cd4ctm1(KOMP)Mbp (more )
Note: Double labeled: red - Gcg; green - Ins1 (assay MGI:6120556) and Ins2 (assay MGI:6120557).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 6B C2cd4C-/- Gcg , 6B C2cd4C-/- Merge Normal expression was detected.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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