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Gene Expression Data
Assay Details
Assay
Reference: J:257228 Li S, et al., Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6120500
Gene symbol: Mapk1
Gene name: mitogen-activated protein kinase 1
Antibody: anti-p-ERK1/2 (Thr202/Tyr204)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 13.5 (more )
Note: Bud stage.
Structure Level Pattern Image Note
TS21: tooth bud Present Regionally restricted 4A
TS21: oral epithelium Strong 4A
TS21: tooth epithelium Absent 4A
TS21: tooth mesenchyme Absent 4A
Specimen 4B: embryonic day 14.5 (more )
Note: Cap stage.
Structure Level Pattern Image Note
TS22: cap stage tooth Present Regionally restricted 4B
TS22: dental papilla Strong 4B
TS22: stellate reticulum Moderate 4B
TS22: cervical loop Absent 4B
TS22: inner enamel epithelium Absent 4B
TS22: outer enamel epithelium Absent 4B
TS22: primary enamel knot Absent 4B
Specimen 4C: embryonic day 16.5 (more )
Note: Bell stage.
Structure Level Pattern Image Note
TS24: bell stage tooth Present Regionally restricted 4C
TS24: dental papilla Strong 4C
TS24: stellate reticulum Moderate 4C
TS24: cervical loop Absent 4C
TS24: inner enamel epithelium Absent 4C
TS24: outer enamel epithelium Absent 4C
TS24: secondary enamel knot Absent 4C
TS24: stratum intermedium Absent 4C
Specimen 4D: postnatal day 0.5 (more )
Note: Presecretory stage.
Structure Level Pattern Image Note
TS27: tooth Present Regionally restricted 4D
Specimen 4E: postnatal day 0.5 (more )
Note: Presecretory stage.
Structure Level Pattern Image Note
TS27: outer enamel epithelium Strong 4E
TS27: stellate reticulum Strong 4E
Specimen 4F: postnatal day 0.5 (more )
Note: Presecretory stage.
Structure Level Pattern Image Note
TS27: dental pulp Strong 4F
TS27: stratum intermedium Strong 4F
TS27: enamel organ Present Regionally restricted 4F No expression in preameloblasts.
TS27: dental papilla Absent 4F No expression in odontoblasts.
Specimen 4G: postnatal day 3.5 (more )
Note: Secretory stage.
Structure Level Pattern Image Note
TS27: tooth Present Regionally restricted 4G
Specimen 4H: postnatal day 3.5 (more )
Note: Secretory stage.
Structure Level Pattern Image Note
TS27: stellate reticulum Strong 4H
TS27: outer enamel epithelium Weak 4H
TS27: stratum intermedium Weak 4H
TS27: enamel organ Present Regionally restricted 4H No expression in secondary ameloblasts.
Specimen 4I: postnatal day 3.5 (more )
Note: Secretory stage.
Structure Level Pattern Image Note
TS27: dental pulp Strong 4I
TS27: dental papilla Absent 4I No expression in odontoblasts.
TS27: enamel organ Present Regionally restricted 4I No expression in secondary ameloblasts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory