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Gene Expression Data
Assay Details
Assay
Reference: J:257228 Li S, et al., Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6120497
Gene symbol: Tgfb1
Gene name: transforming growth factor, beta 1
Antibody: anti-TGFbeta1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 13.5 (more )
Note: Bud stage.
Structure Level Pattern Image Note
TS21: tooth bud Present Regionally restricted 1A
TS21: oral epithelium Strong 1A
TS21: tooth epithelium Strong 1A
TS21: tooth mesenchyme Strong 1A
Specimen 1B: embryonic day 14.5 (more )
Note: Cap stage.
Structure Level Pattern Image Note
TS22: cap stage tooth Present Regionally restricted 1B
TS22: cervical loop Strong 1B
TS22: inner enamel epithelium Strong 1B
TS22: outer enamel epithelium Strong 1B
TS22: primary enamel knot Strong 1B
TS22: stellate reticulum Moderate 1B
TS22: dental papilla Strong 1B
Specimen 1C: embryonic day 16.5 (more )
Note: Bell stage.
Structure Level Pattern Image Note
TS24: bell stage tooth Present Regionally restricted 1C
TS24: cervical loop Strong 1C
TS24: inner enamel epithelium Strong 1C
TS24: outer enamel epithelium Strong 1C
TS24: secondary enamel knot Strong 1C
TS24: stellate reticulum Strong 1C
TS24: stratum intermedium Strong 1C
TS24: dental papilla Strong 1C
Specimen 1D: postnatal day 0.5 (more )
Note: Presecretory stage.
Structure Level Pattern Image Note
TS27: tooth Present Regionally restricted 1D
Specimen 1E: postnatal day 0.5 (more )
Note: Presecretory stage.
Structure Level Pattern Image Note
TS27: outer enamel epithelium Strong 1E
TS27: stellate reticulum Weak 1E
Specimen 1F: postnatal day 0.5 (more )
Note: Presecretory stage.
Structure Level Pattern Image Note
TS27: stratum intermedium Strong 1F
TS27: enamel organ Strong Regionally restricted 1F Strong expression in preameloblasts.
TS27: dental papilla Strong Regionally restricted 1F Strong expression in odontoblasts
TS27: dental pulp Moderate 1F
Specimen 1G: postnatal day 3.5 (more )
Note: Secretory stage.
Structure Level Pattern Image Note
TS27: tooth Present Regionally restricted 1G
Specimen 1H: postnatal day 3.5 (more )
Note: Secretory stage.
Structure Level Pattern Image Note
TS27: enamel organ Strong 1H
TS27: outer enamel epithelium Strong 1H
TS27: stellate reticulum Strong 1H
TS27: stratum intermedium Strong 1H
Specimen 1I: postnatal day 3.5 (more )
Note: Secretory stage.
Structure Level Pattern Image Note
TS27: dental papilla Strong Regionally restricted 1I Strong expression in odontoblasts.
TS27: dental pulp Strong 1I
TS27: enamel organ Strong Regionally restricted 1I Strong expression in secretory ameloblasts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory