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Gene Expression Data
Assay Details
Assay
Reference: J:100306 Ferland RJ, et al., Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma. Brain Res. 2005 Aug 23;1054(1):9-21
Assay type: RNA in situ
MGI Accession ID: MGI:6119716
Gene symbol: Arhgdia
Gene name: Rho GDP dissociation inhibitor alpha
Probe: Rho-GDIalpha cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6a: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Weak Ubiquitous 6a
TS22: cortical plate Present 6a Highest expression in the lateral aspects.
TS22: brain ventricular layer Present 6a Slightly increased expression.

Specimen 6b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brain Weak 6b Relatively low expression.
TS24: cortical plate Strong Regionally restricted 6b High expression in the lateral aspects.
TS24: brain ventricular layer Present 6b Decreased expression.
TS24: cerebral cortex intermediate zone Weak 6b A relative paucity of expression.

Specimen 6c: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: cortical plate Strong Regionally restricted 6c Especially the upper half. Low expression in the lower half. TS27: cortical subplate Strong Not Specified 6c' (Image)
TS27: cortical subplate Strong 6c
TS27: corpus striatum Weak 6c

Specimen 6c': postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: cortical plate Strong Regionally restricted 6c' Especially the upper half. Low expression in the lower half.
TS27: cortical subplate Strong 6c'

Specimen 6c": postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Strong 6c"
TS27: hippocampus CA3 Strong 6c"
TS27: dentate gyrus Weak 6c"

Specimen 6d': postnatal day 3.5 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present Regionally restricted 6d' Slightly higher expression in the middle of the cortical plate.
TS27: cortical subplate Strong 6d'

Specimen 6d": postnatal day 3.5 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Strong 6d"
TS27: hippocampus CA3 Strong 6d"
TS27: dentate gyrus Trace 6d" Very little expression.

Specimen 6e': postnatal day 15.5 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 6e' Especially in the lower layers.
TS28: cortical layer III Strong 6e' Especially in the lower layers.
TS28: cortical layer IV Strong 6e' Especially in the lower layers.
TS28: cortical layer V Strong 6e' Especially in the lower layers.
TS28: cortical layer VI Strong 6e' Especially in the lower layers.

Specimen 6e": postnatal day 15.5 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 6e"
TS28: hippocampus CA3 Present 6e"
TS28: hippocampus Present Widespread 6e"

Specimen 7b: postnatal (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 7b
TS28: cortical layer III Present 7b
TS28: cortical layer IV Present 7b
TS28: cortical layer V Present 7b
TS28: cortical layer VI Present 7b
TS28: hippocampus CA1 Strong 7b
TS28: hippocampus CA3 Strong 7b
TS28: dentate gyrus Weak 7b

Specimen 8 WT upper: postnatal (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 8_upper left
TS28: cortical layer III Present 8_upper left
TS28: cortical layer IV Present 8_upper left
TS28: cortical layer V Present 8_upper left
TS28: cortical layer VI Present 8_upper left

Specimen 8 -/- upper: postnatal (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 8_upper right Same as in the wild-type.
TS28: cortical layer III Present 8_upper right Same as in the wild-type.
TS28: cortical layer IV Present 8_upper right Same as in the wild-type.
TS28: cortical layer V Present 8_upper right Same as in the wild-type.
TS28: cortical layer VI Present 8_upper right Same as in the wild-type.

Specimen 8 WT lower: postnatal (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 8_lower left
TS28: hippocampus CA3 Strong 8_lower left

Specimen 8 -/- lower: postnatal (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 8_lower right Same as in the wild-type.
TS28: hippocampus CA3 Strong 8_lower right Same as in the wild-type.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cortical layer IV Strong
TS28: cortical layer V Strong
TS28: cortical layer VI Strong

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Present Same as in in adult Swiss Webster mice.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory