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Gene Expression Data
Assay Details
Assay
Reference: J:87407 Dudas M, et al., Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway. Dev Biol. 2004 Feb 1;266(1):96-108
Assay type: RNA in situ
MGI Accession ID: MGI:6117824
Gene symbol: Acvr1
Gene name: activin A receptor, type 1
Probe: Alk-2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4e: embryonic day 14.5 (more )
Note: Anterior palatal shelves, before contact.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4e Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4e Expression in oral or nasal palatal epithelium. Less intense expression in medial edge epithelium (MEE) before contact of palatal shelves.
Specimen 4f: embryonic day 14.5 (more )
Note: Anterior palatal shelves, during fusion.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4f Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4f Expression in oral or nasal palatal epithelium. Expression in midline epithelial seam (MEE) during fusion
Specimen 4g: embryonic day 14.5 (more )
Note: Posterior palatal shelves, before contact.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4g Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4g Expression in oral or nasal palatal epithelium. Less intense expression in medial edge epithelium (MEE) before contact of palatal shelves.
Specimen 4h: embryonic day 14.5 (more )
Note: Posterior palatal shelves, during fusion.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4h Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4h Expression in oral or nasal palatal epithelium. Expression in midline epithelial seam (MEE) during fusion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory