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Gene Expression Data
Assay Details
Assay
Reference: J:87407 Dudas M, et al., Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway. Dev Biol. 2004 Feb 1;266(1):96-108
Assay type: RNA in situ
MGI Accession ID: MGI:6117823
Gene symbol: Acvrl1
Gene name: activin A receptor, type II-like 1
Probe: Alk-1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4a: embryonic day 14.5 (more )
Note: Anterior palatal shelves, before contact.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4a Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4a Expression in oral or nasal palatal epithelium. Less intense expression in medial edge epithelium (MEE) before contact of palatal shelves.
Specimen 4b: embryonic day 14.5 (more )
Note: Anterior palatal shelves, during fusion.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4b Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4b Expression in oral or nasal palatal epithelium. Expression in midline epithelial seam (MEE) during fusion.
Specimen 4c: embryonic day 14.5 (more )
Note: Posterior palatal shelves, before contact.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4c Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4c Expression in oral or nasal palatal epithelium. Less intense expression in medial edge epithelium (MEE) before contact of palatal shelves.
Specimen 4d: embryonic day 14.5 (more )
Note: Posterior palatal shelves, during fusion.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 4d Expression predominantly in palatal mesenchyme.
TS22: palatal shelf epithelium Present Regionally restricted 4d Expression in oral or nasal palatal epithelium. Expression in midline epithelial seam (MEE) during fusion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory