Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Tbx21-dre,-Thy1)#Xzhou
Name:	transgene insertion, Xuyu Zhou
MGI ID:	MGI:6117460
Synonyms:	T-bet-Dre-Thy1.1
Transgene:	Tg(Tbx21-dre,-Thy1)#Xzhou  Location: unknown
Alliance:	Tg(Tbx21-dre,-Thy1)#Xzhou page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inserted expressed sequence, Recombinase) Mutation:    Insertion   Tg(Tbx21-dre,-Thy1)#Xzhou expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Tbx21 (MGI:1888984)   Mutation details: Transgene consists of the Dre-2A-Thy1.1 fusion DNA fragment inserted into the ATG translational start site of a 182kb BAC clone (RP23-451G13) bearing the entire mouse Tbx21 locus was used. The modified BAC was purified and microinjected into the pronuclei of a mouse fertilized ovum to generate transgenic line of mice. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:252233)

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx21 (mouse) Summary of all recombinase alleles driven by Tbx21. Alliance mouse Tbx21 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:252233 Zhang Z, et al., Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability. J Immunol. 2017 Apr 01;198(7):2612-2625
All:	1 reference(s)