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Gene Expression Data
Assay Details
Assay
Reference: J:218261 Freeman SD, et al., Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development. Dev Dyn. 2015 Feb;244(2):168-80
Assay type: RNA in situ
MGI Accession ID: MGI:6117324
Gene symbol: Sulf1
Gene name: sulfatase 1
Probe: Sulf1 cDNA5
Probe preparation: Antisense RNA
Results
Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear Present Regionally restricted 7A Expression is in the ventro-lateral wall of the otocyst.
TS20: floor plate Present 7A
Specimen 7B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea Present 7B
TS22: cochlear ganglion Weak 7B
Specimen 7B': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlear duct Strong Regionally restricted 7B' Expression is in the roof and in an anteromedial portion of the medial wall.
Specimen 7C: embryonic day 17.5 (more )
Note: Double labeled: blue - Sulf1; white - Myo7a (assay MGI:6117315).
Structure Level Pattern Image Note
TS25: semicircular canal Present Regionally restricted 7C'' , 7C Expression is in the hair cells of the cristae.
TS25: utricle Present Regionally restricted 7C'' , 7C Expression is in the hair cells.
Specimen 7D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cochlear ganglion Present 7D
TS25: cochlea Present Regionally restricted 7D Expression is in the lateral wall throughout the length of the cochlea.
Specimen 7D': embryonic day 17.5 (more )
Note: Double labeled: blue - Sulf1; white - Myo7a (assay MGI:6117315).
Structure Level Pattern Image Note
TS25: cochlea epithelium Present Regionally restricted 7D'' Expression is in the outer hair cells and is absent in the inner hair cells.
Specimen 7E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cochlea Present 7E
TS27: cochlear ganglion Present 7E
Specimen 7E': postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: crista ampullaris Present Regionally restricted 7E' Expression is in the hair cell layers.
Specimen 7E'': postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: saccule epithelium Present Regionally restricted 7E'' Expression is in the hair cell layers.
Specimen 7E''': postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: utricle epithelium Present Regionally restricted 7E''' Expression is in the hair cell layers.
Specimen 7E'''': postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cochlea epithelium Present Regionally restricted 7E'''' Expression is in the inner and outer hair cells.
TS27: vestibular membrane Present Regionally restricted 7E'''' Expression is in the epithelial cell layer of the Reissner's membrane.
TS27: stria vascularis Present Regionally restricted 7E'''' Expression is in the marginal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory