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Tg(Fabp-Gtf2ird1)1Kajim
Transgene Detail
Summary
Symbol: Tg(Fabp-Gtf2ird1)1Kajim
Name: transgene insertion 1, Shingo Kajimura
MGI ID: MGI:6117140
Synonyms: Gtf2ird1 Tg
Transgene: Tg(Fabp-Gtf2ird1)1Kajim  Location: unknown  
Alliance: Tg(Fabp-Gtf2ird1)1Kajim page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsVariant 5 of mouse Gtf2ird1 (NM_001081465.1) is driven by the Fabp4 promoter/enhancer in adipose tissues. Gtf2ird1 mRNA and protein expression levels in the BAT and WAT transgenic mice are significantly elevated compared with those of littermate controls. (J:256864)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:256864 Hasegawa Y, et al., Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis. Cell Metab. 2018 Jan 9;27(1):180-194.e6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory