Kctd13 Western blot Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:250125 Escamilla CO, et al., Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231
Assay type:	Western blot
MGI Accession ID:	MGI:6115525
Gene symbol:	Kctd13
Gene name:	potassium channel tetramerisation domain containing 13

Antibody:

anti-Kctd13 (HPA043524)

Results

Image: 1b KCTD13

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
WT Hippocampus	P adult	TS28: hippocampus	Present	involves: C57BL/6 * C57BL/6J		Not Specified
HET Hippocampus	P adult	TS28: hippocampus	Weak (a)	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13⁺	Not Specified
KO Hippocampus	P adult	TS28: hippocampus	Absent	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13^{tm1.1(KOMP)Vlcg}	Not Specified
WT Cortex	P adult	TS28: cerebral cortex	Present	involves: C57BL/6 * C57BL/6J		Not Specified
HET Cortex	P adult	TS28: cerebral cortex	Weak (a)	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13⁺	Not Specified
KO Cortex	P adult	TS28: cerebral cortex	Absent	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13^{tm1.1(KOMP)Vlcg}	Not Specified
WT Cerebellum	P adult	TS28: cerebellum	Present	involves: C57BL/6 * C57BL/6J		Not Specified
HET Cerebellum	P adult	TS28: cerebellum	Weak (a)	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13⁺	Not Specified
KO Cerebellum	P adult	TS28: cerebellum	Absent	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13^{tm1.1(KOMP)Vlcg}	Not Specified
WT Midbrain	P adult	TS28: midbrain	Present	involves: C57BL/6 * C57BL/6J		Not Specified
HET Midbrain	P adult	TS28: midbrain	Weak (a)	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13⁺	Not Specified
KO Midbrain	P adult	TS28: midbrain	Absent	involves: C57BL/6J * C57BL/6NTac	Kctd13^{tm1.1(KOMP)Vlcg}/Kctd13^{tm1.1(KOMP)Vlcg}	Not Specified

Notes:
(a) Approximately 50% decrease in expression in heterozygotes compared to wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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