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Gene Expression Data
Assay Details
Assay
Reference: J:251844 Zamboni V, et al., Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits. Sci Rep. 2016 Oct 7;6:34877
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6115351
Gene symbol: Calb2
Gene name: calbindin 2
Antibody: anti-Calretinin
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2a Wild-type: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 2a Wild-type

Specimen 2a ArhGAP15-/-: postnatal adult; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 2a ArhGAP15-/- Authors report a reduced number of expressing neurons in mutant compared with wild type.

Specimen not shown Wild-type: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present

Specimen not shown ArhGAP15-/-: postnatal adult; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: hippocampus Present No difference in the number of expressing neurons in the CA1-CA3 regions.

Specimen 3e: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: hippocampus Present Regionally restricted 3e

Specimen 3e': embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: hippocampus Present Regionally restricted 3e' Expression in tangentially migrating immature neurons.

Specimen 3e": embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: hippocampus Present Regionally restricted 3e" Expression in tangentially migrating immature neurons.

Specimen 3f: embryonic day 17.5; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS25: hippocampus Present Regionally restricted 3f Authors report there was no difference in the total number of expression cells or in their distribution.

Specimen 3f': embryonic day 17.5; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS25: hippocampus Present Regionally restricted 3f' Authors state that expressing cells in mutant deviate more than in wild-type.

Specimen 3f": embryonic day 17.5; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS25: hippocampus Present Regionally restricted 3f" Authors state that expressing cells in mutant deviate more than in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory