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Gene Expression Data
Assay Details
Assay
Reference: J:251844 Zamboni V, et al., Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits. Sci Rep. 2016 Oct 7;6:34877
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6115245
Gene symbol: Arhgap15
Gene name: Rho GTPase activating protein 15
Reporter: lacZ
Direct Detection
Results
Specimen E13.5 not shown: embryonic day 13.5; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS21: telencephalon Ambiguous Authors state that no expression was observed prior to E13.5
Specimen E14.5 not shown: embryonic day 14.5; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Expression detected in cortical and hippocampal primordia.
TS22: hippocampus Present Expression detected in cortical and hippocampal primordia.
TS22: ganglionic eminence Absent
Specimen E15.5 not shown: embryonic day 15.5; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Expression detected in cortical and hippocampal primordia.
TS23: hippocampus Present Expression detected in cortical and hippocampal primordia.
TS23: ganglionic eminence Absent
Specimen 1f: postnatal day 2; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS27: hippocampus Present 1f
TS27: main olfactory bulb Present 1f
TS27: neocortex Present 1f
Specimen 1g: postnatal day 60; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb granule cell layer Present 1g
TS28: main olfactory bulb mitral cell layer Present 1g
TS28: main olfactory bulb Present Regionally restricted 1g Expression in periglomerular neurons.
Specimen 1h: postnatal day 60; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: somatosensory cortex Present 1h
Specimen 1i: postnatal day 60; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 1i Expression in pyramidal layer of CA1-CA3 regions and in the dentate gyrus.
TS28: CA2 pyramidal cell layer Present 1i Expression in pyramidal layer of CA1-CA3 regions and in the dentate gyrus.
TS28: CA3 pyramidal cell layer Present 1i Expression in pyramidal layer of CA1-CA3 regions and in the dentate gyrus.
TS28: dentate gyrus Present 1i Expression in pyramidal layer of CA1-CA3 regions and in the dentate gyrus.
Specimen S1c: postnatal adult; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Note: Double labeled: blue - Arhgap15 reporter; brown - Gad1 (GAD67; assay MGI:6115349).
Structure Level Pattern Image Note
TS28: hippocampus Present S1c Expression in most pyramidal cells and GABAergic interneurouns.
Specimen S1d: postnatal adult; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Note: Double labeled: blue - Arhgap15 reporter; brown - Gad1 (GAD67; assay MGI:6115349).
Structure Level Pattern Image Note
TS28: hippocampus Present S1d Expression in most pyramidal cells and GABAergic interneurouns.
Specimen S1e: postnatal adult; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Note: Double labeled: blue - Arhgap15 reporter; brown - Gad1 (GAD67; assay MGI:6115349).
Structure Level Pattern Image Note
TS28: hippocampus Present S1e Expression in most pyramidal cells and GABAergic interneurouns.
Specimen S1f: postnatal adult; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Note: Double labeled: blue - Arhgap15 reporter; brown - Gad1 (GAD67; assay MGI:6115349).
Structure Level Pattern Image Note
TS28: dentate gyrus Present S1f Expression in most pyramidal cells and GABAergic interneurouns.
Specimen S1g: postnatal adult; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Note: Double labeled: blue - Arhgap15 reporter; brown - Gad1 (GAD67; assay MGI:6115349).
Structure Level Pattern Image Note
TS28: dentate gyrus Present S1g Expression in most pyramidal cells and GABAergic interneurouns.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory