Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Trpc4-cre)383Stl
Name:	transgene insertion 383, Susumu Tonegawa
MGI ID:	MGI:6114650
Synonyms:	Trpc4-Cre
Transgene:	Tg(Trpc4-cre)383Stl  Location: unknown
Alliance:	Tg(Trpc4-cre)383Stl page

Strain of Origin:

C57BL/6J

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Trpc4-cre)383Stl expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Trpc4 (MGI:109525)   Mutation details: The nuclear localization sequence (NLS)-cre-poly A-FRT-amp-FRT cassette was inserted using Red/ET recombination techniques into the translation initiation site located in the 2nd exon of the mouse Trpc4 gene in a BAC clone RP24-67D9. Resistant clones were selected and confirmed for appropriate homologous recombination, after which amp was removed prior to the microinjection. The resulting vector was purified, linearized and microinjected into pronuclei of fertilized C57BL/6J eggs. The founder G was crossed with C57BL6J mice and the subline 383 was crossed with C57BL6J mice. (J:255267)

Activity:	Tissue activity of this recombinase allele
Driver:	Trpc4 (mouse) Summary of all recombinase alleles driven by Trpc4. Alliance mouse Trpc4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:255267 Okuyama T, et al., Ventral CA1 neurons store social memory. Science. 2016 Sep 30;353(6307):1536-1541
All:	4 reference(s)