Gene Expression Data
Assay Details
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Assay
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Reference:
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J:90644
Spieler D, et al., Involvement of Pax6 and Otx2 in the forebrain-specific regulation of the vertebrate homeobox gene ANF/Hesx1. Dev Biol. 2004 May 15;269(2):567-79
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6113710
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Gene symbol:
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Hesx1
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Gene name:
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homeobox gene expressed in ES cells
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Probe:
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Hesx1 probe12
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
not shown E7 Pax6+/+:
embryonic day 7.0
(more  )
Specimen
not shown E7 Pax6+/+:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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Not Specified
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: embryo |
Present |
Regionally restricted |
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Authors describe an anterior domain of expression.
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Specimen
not shown E7 Pax6-/-:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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Not Specified
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: embryo |
Present |
Regionally restricted |
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Expression resembled the wild-type pattern.
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Specimen
6A:
embryonic day 8.25
(more )
Specimen
6A:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 8.25
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
6B:
embryonic day 8.25
(more )
Specimen
6B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 8.25
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
6C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 8.25
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: future brain neural fold |
Present |
Regionally restricted |
6C
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Authors report a slight difference in the expression domain of mutant mice compared to that of wild-type. Marginal broadening of the anterior neural fold domain.
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 8.25
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: future brain neural fold |
Present |
Regionally restricted |
6D
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Authors report a slight difference in the expression domain of mutant mice compared to that of wild-type. Marginal broadening of the anterior neural fold domain.
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Specimen
6E:
embryonic day 10.0
(more )
Specimen
6E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: oral region ectoderm |
Weak |
Regionally restricted |
6E
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Weak domain in ventral medial part of telencephalon and oral ectoderm.
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| TS16: telencephalon |
Weak |
Regionally restricted |
6E
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Weak domain in ventral medial part of telencephalon and oral ectoderm.
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Specimen
6F:
embryonic day 10.0
(more )
Specimen
6F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: oral region ectoderm |
Weak |
Regionally restricted |
6F
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Weak domain in ventral medial part of telencephalon and oral ectoderm.
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| TS16: telencephalon |
Weak |
Regionally restricted |
6F
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Weak domain in ventral medial part of telencephalon and oral ectoderm.
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Specimen
6G:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: oral region ectoderm |
Present |
Regionally restricted |
6G
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Enlargement of expression domain compared to that of wild type.
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| TS16: telencephalon |
Present |
Regionally restricted |
6G
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Enlargement of expression domain compared to that of wild type.
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| TS16: diencephalon |
Present |
Regionally restricted |
6G
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Expression is extended dorsally into the ventral diencephalon and laterally into the optic stalks.
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| TS16: optic stalk |
Present |
Regionally restricted |
6G
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Expression is extended dorsally into the ventral diencephalon and laterally into the optic stalks.
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Specimen
6H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: oral region ectoderm |
Present |
Regionally restricted |
6H
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Enlargement of expression domain compared to that of wild type.
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| TS16: telencephalon |
Present |
Regionally restricted |
6H
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Enlargement of expression domain compared to that of wild type.
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| TS16: diencephalon |
Present |
Regionally restricted |
6H
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Expression is extended dorsally into the ventral diencephalon and laterally into the optic stalks.
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| TS16: optic stalk |
Present |
Regionally restricted |
6H
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Expression is extended dorsally into the ventral diencephalon and laterally into the optic stalks.
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