Pvalbtm1.1(Ncre)Mdes
Targeted Allele Detail
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| Symbol: |
Pvalbtm1.1(Ncre)Mdes |
| Name: |
parvalbumin; targeted mutation 1.1, Martin Deschenes |
| MGI ID: |
MGI:6113615 |
| Synonyms: |
Pv-CreN |
| Gene: |
Pvalb Location: Chr15:78075314-78090600 bp, - strand Genetic Position: Chr15, 36.93 cM, cytoband E
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| Alliance: |
Pvalbtm1.1(Ncre)Mdes page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:253250
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Recombinase) |
| Mutation: |
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Insertion
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Pvalbtm1.1(Ncre)Mdes expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Pvalb (MGI:97821) |
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Mutation details: Mice were generated by inserting a 2A sequence, the N-terminal fragment of cre recombinase (aa 19-59) fused to the intein-N peptide fragment (123 N terminal amino acids of the DnaE split intein sequence) and Frt-flanked PGK-neomycin resistance cassette immediately in front of the stop codon of parvalbumin coding sequence by homologous recombination. The Frt-flanked PGK-neomycin resistance cassette was removed by crossing with transgenic mice expressing Flpo.
(J:253250)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Pvalb
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pvalb Mutation: |
29 strains or lines available
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| Original: |
J:253250 Bellavance MA, et al., Parallel Inhibitory and Excitatory Trigemino-Facial Feedback Circuitry for Reflexive Vibrissa Movement. Neuron. 2017 Aug 2;95(3):673-682.e4 |
| All: |
2 reference(s) |
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Analysis Tools
