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Tg(Thy1-SNCA*Y39C)5Crf
Transgene Detail
Summary
Symbol: Tg(Thy1-SNCA*Y39C)5Crf
Name: transgene insertion 5, Curt R Freed
MGI ID: MGI:6113614
Synonyms: line B5365
Transgene: Tg(Thy1-SNCA*Y39C)5Crf  Location: unknown  
Alliance: Tg(Thy1-SNCA*Y39C)5Crf page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Thy1-SNCA*Y39C)5Crf expresses 1 gene
    Transgenic mice express a Y39C mutant human alpha-synuclein variant under the murine Thy1 promoter. (J:135332)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:135332 Zhou W, et al., Transgenic mice overexpressing tyrosine-to-cysteine mutant human alpha-synuclein: a progressive neurodegenerative model of diffuse Lewy body disease. J Biol Chem. 2008 Apr 11;283(15):9863-70
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory