Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tbx18tm3.1(cre/ERT2)Sev
Name:	T-box18; targeted mutation 3.1, Sylvia Evans
MGI ID:	MGI:6113477
Synonyms:	Tbx18-CreERT2
Gene:	Tbx18  Location: Chr9:87584853-87613313 bp, - strand  Genetic Position: Chr9, 47.06 cM, cytoband E3.2
Alliance:	Tbx18tm3.1(cre/ERT2)Sev page

Germline Transmission:	Earliest citation of germline transmission: J:253913
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Null/knockout, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tbx18tm3.1(cre/ERT2)Sev expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tbx18 (MGI:1923615)   Mutation details: A Cre/ERT2_FRT_PGK-Neo_FRT cassette was inserted into the Tbx18 locus, 6 base pairs downstream of the endogenous ATG. The neo cassette was removed by FLP mediated recombination. (J:253913)

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx18 (mouse) Summary of all recombinase alleles driven by Tbx18. Alliance mouse Tbx18 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tbx18 Mutation:	36 strains or lines available

Original:	J:253913 Guimaraes-Camboa N, et al., Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017 Mar 2;20(3):345-359.e5
All:	6 reference(s)