Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nyap2tm1Tya
Name:	neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2; targeted mutation 1, Tadashi Yamamoto
MGI ID:	MGI:6107632
Gene:	Nyap2  Location: Chr1:81054667-81319479 bp, + strand  Genetic Position: Chr1, 41.75 cM
Alliance:	Nyap2tm1Tya page

Germline Transmission:	Earliest citation of germline transmission: J:180006
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The genomic sequence that includes sequence for exon 4, encoding the NHM motifs, was replaced with a neomycin resistance gene cassette. (J:180006)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Nyap2 Mutation:	35 strains or lines available

Original:	J:180006 Yokoyama K, et al., NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54
All:	1 reference(s)