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Eya1tm3(cre/ERT2)Px
Targeted Allele Detail
Summary
Symbol: Eya1tm3(cre/ERT2)Px
Name: EYA transcriptional coactivator and phosphatase 1; targeted mutation 3, Pin-Xian Xu
MGI ID: MGI:6102917
Synonyms: Eya1-CreERT2
Gene: Eya1  Location: Chr1:14239178-14380459 bp, - strand  Genetic Position: Chr1, 4.31 cM
Alliance: Eya1tm3(cre/ERT2)Px page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:250210
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intergenic deletion
 
Eya1tm3(cre/ERT2)Px expression driven by 1 gene
 
Mutation detailsThe endogenous start codon as well as the exon 1 was replaced with an ATG-CreERT2-poly(A) cassette and a PGK-neo gene. (J:250210)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Eya1 (mouse)
Summary of all recombinase alleles driven by Eya1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eya1 Mutation:  54 strains or lines available
References
Original:  J:250210 Xu J, et al., Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis. Dev Cell. 2014 Nov 24;31(4):434-47
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory