Eya1tm3(cre/ERT2)Px
Targeted Allele Detail
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Symbol: |
Eya1tm3(cre/ERT2)Px |
Name: |
EYA transcriptional coactivator and phosphatase 1; targeted mutation 3, Pin-Xian Xu |
MGI ID: |
MGI:6102917 |
Synonyms: |
Eya1-CreERT2 |
Gene: |
Eya1 Location: Chr1:14239178-14380459 bp, - strand Genetic Position: Chr1, 4.31 cM
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Alliance: |
Eya1tm3(cre/ERT2)Px page
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Germline Transmission: |
Earliest citation of germline transmission:
J:250210
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intergenic deletion
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Eya1tm3(cre/ERT2)Px expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The endogenous start codon as well as the exon 1 was replaced with an ATG-CreERT2-poly(A) cassette and a PGK-neo gene.
(J:250210)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Eya1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Eya1 Mutation: |
54 strains or lines available
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Original: |
J:250210 Xu J, et al., Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis. Dev Cell. 2014 Nov 24;31(4):434-47 |
All: |
8 reference(s) |
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