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Tg(CD3E)#Alat
Transgene Detail
Summary
Symbol: Tg(CD3E)#Alat
Name: transgene insertion, Alan Tunnacliffe
MGI ID: MGI:6098724
Synonyms: hCD3epsilon
Transgene: Tg(CD3E)#Alat  Location: unknown  
Alliance: Tg(CD3E)#Alat page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD3E)#Alat expresses 1 gene
 
Mutation detailsHuman cosmid cEpsilon1, containing the CD3E gene, was injected into BDF2 fertilized oocytes. Five independent lines were established: three low copy and two high copy number. Northern blot analysis showed that the human gene was expressed in the correct T cell-specific manner in all lines. (J:172562)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:249821 Tunnacliffe A, et al., The majority of human CD3 epitopes are conferred by the epsilon chain. Int Immunol. 1989;1(5):546-50
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory