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Tg(CD3E)41Alat
Transgene Detail
Summary
Symbol: Tg(CD3E)41Alat
Name: transgene insertion 41, Alan Tunnacliffe
MGI ID: MGI:6098742
Synonyms: hCD3epsilon TG41
Transgene: Tg(CD3E)41Alat  Location: unknown  
Alliance: Tg(CD3E)41Alat page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD3E)41Alat expresses 1 gene
 
Mutation detailsHuman cosmid cEpsilon1, containing the CD3E gene, was injected into BDF2 fertilized oocytes. Five independent lines were established: three low copy and two high copy number. This allele represents a low copy number with 5 transgene insertions. Northern blot analysis showed that the human gene was expressed in the correct T cell-specific manner. (J:172562)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:172562 de la Hera A, et al., Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex. J Exp Med. 1991 Jan 1;173(1):7-17
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory