Tg(CD3E)21Alat
Transgene Detail
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| Symbol: |
Tg(CD3E)21Alat |
| Name: |
transgene insertion 21, Alan Tunnacliffe |
| MGI ID: |
MGI:6098739 |
| Synonyms: |
hCD3epsilon TG21 |
| Transgene: |
Tg(CD3E)21Alat Location: unknown
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| Alliance: |
Tg(CD3E)21Alat page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CD3E)21Alat expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CD3E (916) |
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Mutation details: Human cosmid cEpsilon1, containing the CD3E gene, was injected into BDF2 fertilized oocytes. Five independent lines were established: three low copy and two high copy number. This allele represents a low copy number with 3 transgene insertions. Northern blot analysis showed that the human gene was expressed in the correct T cell-specific manner.
(J:172562)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:172562 de la Hera A, et al., Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex. J Exp Med. 1991 Jan 1;173(1):7-17 |
| All: |
1 reference(s) |
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Analysis Tools
