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Gene Expression Data
Assay Details
Assay
Reference: J:127109 Schnichels S, et al., Gene expression of the repulsive guidance molecules/neogenin in the developing and mature mouse visual system: C57BL/6J vs. the glaucoma model DBA/2J. Gene Expr Patterns. 2007 Dec;8(1):1-11
Assay type: RNA in situ
MGI Accession ID: MGI:6098713
Gene symbol: Neo1
Gene name: neogenin
Probe: Neo1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1G: embryonic day 14.5 (more )
Note: Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
Structure Level Pattern Image Note
TS22: retina Present Graded 1G Gradient of expression decreasing from inside to outside of developing retina.
Specimen 1H: postnatal day 0 (more )
Note: Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
Structure Level Pattern Image Note
TS27: retina layer Present Regionally restricted 1H Expression in every layer of developing retina except for inner plexiform layer.
TS27: retina inner plexiform layer Absent 1H
Specimen 1I: postnatal day 10 (more )
Note: Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 1I
TS28: retina inner nuclear layer Present 1I
TS28: retina outer nuclear layer Present Regionally restricted 1I Expression to a lesser extent in the outer nuclear layer. Higher expression in tissue close to outer limiting membrane.
Specimen 5A: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: retina Present 5A Stronger expression in C57BL/6J than in DBA/2J mice (not yet affected by glaucoma).
Specimen 5B: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: retina Weak 5B Lower expression in DBA/2J compared to C57GL/6J mice.
Specimen 5C: postnatal month 15 (more )
Structure Level Pattern Image Note
TS28: retina Strong 5C Expression increased compared to earlier time points.
Specimen 5D: postnatal month 15 (more )
Structure Level Pattern Image Note
TS28: retina Very strong 5D Expression increased compared to earlier time points. Stronger expression in DBA/2J than in C57BL6 mice.
Specimen 6B: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: retina Weak Regionally restricted 6B Authors report congruent expression pattern of Rgma and neogenin, with weaker expression of neogenin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory