Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:127109
Schnichels S, et al., Gene expression of the repulsive guidance molecules/neogenin in the developing and mature mouse visual system: C57BL/6J vs. the glaucoma model DBA/2J. Gene Expr Patterns. 2007 Dec;8(1):1-11
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:6098712
|
|
Gene symbol:
|
Rgmb
|
|
Gene name:
|
repulsive guidance molecule family member B
|
|
|
Results
|
Specimen
1D:
embryonic day 14.5
(more  )
Note: Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
Specimen
1D:
(close  )
|
Genetic Background:
|
either: C57BL/6J or DBA/2J
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Trace |
Regionally restricted |
1D
|
Very weak expression in inner tissue of embryonic retina.
|
Specimen
1E:
postnatal day 0
(more )
Note: Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
Specimen
1E:
(close )
|
Genetic Background:
|
either: C57BL/6J or DBA/2J
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
|
Specimen
1F:
postnatal day 10
(more )
Note: Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
Specimen
1F:
(close )
|
Genetic Background:
|
either: C57BL/6J or DBA/2J
|
|
Age:
|
postnatal day 10
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Authors state there were no differences in the expression pattern in the developing retina between C57BL/6J and DBA/2J mice (E14.5, P0 and P10) (data not shown).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: retina ganglion cell layer |
Present |
Spotted |
1F
|
Spotty expression pattern, with expression in ganglion cell layer, inner nuclear layer and outer nuclear layer.
|
| TS28: retina inner nuclear layer |
Present |
Spotted |
1F
|
Spotty expression pattern, with expression in ganglion cell layer, inner nuclear layer and outer nuclear layer.
|
| TS28: retina outer nuclear layer |
Present |
Spotted |
1F
|
Spotty expression pattern, with expression in ganglion cell layer, inner nuclear layer and outer nuclear layer.
|
Specimen
7A:
postnatal month 6
(more )
Specimen
7A:
(close )
|
Genetic Background:
|
C57BL/6J
|
|
Age:
|
postnatal month 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
7B:
postnatal month 6
(more )
Specimen
7B:
(close )
|
Genetic Background:
|
DBA/2J
|
|
Age:
|
postnatal month 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: retina ganglion cell layer |
Strong |
|
7B
|
Higher expression in DBA/2J compared to C57BL/6J mice. 25% more expressing cells in ganglion cell layer, inner nuclear layer and outer nuclear layer as compared to C57BL/6J mice.
|
| TS28: retina inner nuclear layer |
Strong |
|
7B
|
Higher expression in DBA/2J compared to C57BL/6J mice. 25% more expressing cells in ganglion cell layer, inner nuclear layer and outer nuclear layer as compared to C57BL/6J mice.
|
| TS28: retina outer nuclear layer |
Strong |
|
7B
|
Higher expression in DBA/2J compared to C57BL/6J mice. 25% more expressing cells in ganglion cell layer, inner nuclear layer and outer nuclear layer as compared to C57BL/6J mice.
|
Specimen
9A:
postnatal month 6
(more )
Specimen
9A:
(close )
|
Genetic Background:
|
C57BL/6J
|
|
Age:
|
postnatal month 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: optic nerve |
Present |
|
9A
|
No difference in expression intensity between C57BL/6J and age-matched DBA-2J mice.
|
Specimen
9B:
postnatal month 6
(more )
Specimen
9B:
(close )
|
Genetic Background:
|
DBA/2J
|
|
Age:
|
postnatal month 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: optic nerve |
Present |
|
9B
|
No difference in expression intensity between C57BL/6J and age-matched DBA-2J mice.
|
Specimen
9C:
postnatal month 11
(more )
Specimen
9C:
(close )
|
Genetic Background:
|
C57BL/6J
|
|
Age:
|
postnatal month 11
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: optic nerve |
Weak |
|
9C
|
Lower expression than for younger C57BL/6J mice/
|
Specimen
9D:
postnatal month 11
(more )
Specimen
9D:
(close )
|
Genetic Background:
|
DBA/2J
|
|
Age:
|
postnatal month 11
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: optic nerve |
Strong |
|
9D
|
Higher expression than for youger DBA/2J mice. Expression increased about 5-times compared to C57BL/6J mice at the same age.
|
|
Analysis Tools