Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Armc5tm1Jwu
Name:	armadillo repeat containing 5; targeted mutation 1, Jiangping Wu
MGI ID:	MGI:6098706
Gene:	Armc5  Location: Chr7:127836514-127844272 bp, + strand  Genetic Position: Chr7, 70.06 cM
Alliance:	Armc5tm1Jwu page

Germline Transmission:	Earliest citation of germline transmission: J:244662
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A genomic fragment containing exon 13 was replaced by a Neo cassette. RT-PCR experiments showed that expression was abolished in spleen T cells, thymocytes, lymph nodes, brain and adrenal glands. (J:244662)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Armc5 Mutation:	17 strains or lines available

Original:	J:244662 Hu Y, et al., Armc5 deletion causes developmental defects and compromises T-cell immune responses. Nat Commun. 2017 Feb 07;8:13834
All:	1 reference(s)