Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gsdma2tm1(GFP/cre/ERT2)Wtsi
Name:	gasdermin A2; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID:	MGI:6095194
Synonyms:	tm1(EGFP_CreERT2)Wtsi
Gene:	Gsdma2  Location: Chr11:98537585-98548790 bp, + strand  Genetic Position: Chr11, 62.28 cM, cytoband D
Alliance:	Gsdma2tm1(GFP/cre/ERT2)Wtsi page

Mutant Cell Line:	CEPD0108_3_C09
Germline Transmission:	Earliest citation of germline transmission: J:188991
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	EUCOMMTOOLS

Allele Type:    Targeted (Conditional ready, Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Gsdma2tm1(GFP/cre/ERT2)Wtsi expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gsdma2 (MGI:1921490)   Mutation details: According to the vector molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, a Rox-flanked puromycin resistance cassette followed by one loxP site all inserted into the intron just upstream of exon 5, and a single loxP site downstream of exon 7. (J:188991) Inheritance:    Not Specified

Activity:	Tissue activity of this recombinase allele
Driver:	Gsdma2 (mouse) Summary of all recombinase alleles driven by Gsdma2. Alliance mouse Gsdma2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gsdma2 Mutation:	31 strains or lines available

Original:	J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:	1 reference(s)