Tg(KRT10-Nfe2l2)#Swnr
Transgene Detail
|
|
| Symbol: |
Tg(KRT10-Nfe2l2)#Swnr |
| Name: |
transgene insertion, Sabine Werner |
| MGI ID: |
MGI:6095170 |
| Synonyms: |
K10caNrf2 |
| Transgene: |
Tg(KRT10-Nfe2l2)#Swnr Location: unknown
|
| Alliance: |
Tg(KRT10-Nfe2l2)#Swnr page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(KRT10-Nfe2l2)#Swnr expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Nfe2l2 (MGI:108420) |
|
|
| |
|
Mutation details: The transgene comprises the following elements: the bovine keratin 10 promoter, a rabbit beta-globin intron, a cDNA for the constitutively active isoform of the mouse Nfe2l2 gene which lacks sequence for the N-terminal Neh2 domain, and human growth hormone gene poly(A) features. Three mouse lines, with expression levels similar to or lower than the endogenous gene, were established after pronuclear injection of FVB/N fertilized oocytes. The pound # sign is used in the allele symbol because no line was specified.
(J:160519)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:160519 Schafer M, et al., Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis. Genes Dev. 2010 May 15;24(10):1045-58 |
| All: |
1 reference(s) |
|
Analysis Tools
