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Tg(Bmp5-Hmgcll1,Hspa1b-lacZ)1Kng
Transgene Detail
Summary
Symbol: Tg(Bmp5-Hmgcll1,Hspa1b-lacZ)1Kng
Name: transgene insertion 1, David M Kingsley
MGI ID: MGI:6094233
Synonyms: BAC-C-lacZ
Transgene: Tg(Bmp5-Hmgcll1,Hspa1b-lacZ)1Kng  Location: unknown  
Alliance: Tg(Bmp5-Hmgcll1,Hspa1b-lacZ)1Kng page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe linearized BAC clone (RP23-476E23) encodes regulatory elements of mouse Bmp5 (but no coding sequences) and the last two exons of the Hmgcll1 gene; it was co-injected with a minimal hsp68-lacZ reporter. The clone was isolated from the RPCI-23 female (C57BL/6J) mouse BAC library and contains a sequence that controls expression of the medial perichondrium of embryonic ribs. Robust expression is observed at E14.5 dpc. (J:248382)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:248382 Guenther CA, et al., A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury. Bone. 2015 Aug;77:31-41
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory