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Tg(CAG-Srf)HLJfd
Transgene Detail
Summary
Symbol: Tg(CAG-Srf)HLJfd
Name: transgene insertion HL, Jean-Francois Decaux
MGI ID: MGI:5927642
Synonyms: SRF-HL
Transgene: Tg(CAG-Srf)HLJfd  Location: unknown  
Alliance: Tg(CAG-Srf)HLJfd page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(CAG-Srf)HLJfd expresses 1 gene
 
Mutation detailsThe transgene comprises the following elements: the CAG promoter, a loxP site, a bacterial chloramphenicol acetyltransferase (cat) reporter gene, poly(A) features, a loxP site and the mouse serum response factor (Srf) cDNA. The inserted mouse gene will only be expressed after removal of the cat gene through cre-mediated recombination. This line was selected for its high level expression. (J:243527)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:243527 Angelini A, et al., Regulation of Connective Tissue Growth Factor and Cardiac Fibrosis by an SRF/MicroRNA-133a Axis. PLoS One. 2015;10(10):e0139858
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory