Tg(CAG-Srf)HLJfd
Transgene Detail
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Symbol: |
Tg(CAG-Srf)HLJfd |
Name: |
transgene insertion HL, Jean-Francois Decaux |
MGI ID: |
MGI:5927642 |
Synonyms: |
SRF-HL |
Transgene: |
Tg(CAG-Srf)HLJfd Location: unknown
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Alliance: |
Tg(CAG-Srf)HLJfd page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Tg(CAG-Srf)HLJfd expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Srf (MGI:106658) |
Prededed by a floxed cat reporter gene |
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Mutation details: The transgene comprises the following elements: the CAG promoter, a loxP site, a bacterial chloramphenicol acetyltransferase (cat) reporter gene, poly(A) features, a loxP site and the mouse serum response factor (Srf) cDNA. The inserted mouse gene will only be expressed after removal of the cat gene through cre-mediated recombination. This line was selected for its high level expression.
(J:243527)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:243527 Angelini A, et al., Regulation of Connective Tissue Growth Factor and Cardiac Fibrosis by an SRF/MicroRNA-133a Axis. PLoS One. 2015;10(10):e0139858 |
All: |
1 reference(s) |
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