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Gene Expression Data
Assay Details
Assay
Reference: J:18498 Schmidt CJ, et al., G(O), a guanine nucleotide binding protein, is expressed during neurite extension in the embryonic mouse. J Neurosci Res. 1994 Jun 1;38(2):182-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5925241
Gene symbol: Gnao1
Gene name: guanine nucleotide binding protein, alpha O
Antibody: anti-alpha O
Assay notes: Embryos were fixed either with periodate-lysine-paraformaldehyde or in a 9:1 mixture of 4% paraformaldehyde:saturated picric acid.
Results
Specimen E7 not shown: embryonic day 7.0 (more )
Structure Level Pattern Image Note
TS10: embryo Absent
Specimen E8 not shown: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo Absent
Specimen E9 not shown: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: future brain Weak Regionally restricted Faint expression in marginal zone of neural tube at sites of differentiating neurons.
Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon marginal layer Present Regionally restricted 2A Intense expression in first post-mitotic neurons in marginal zone of neuronal tube. Expression in both cytoplasm and emerging neurites.
TS17: Rathke's pouch Present 2A
Specimen 2C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon marginal layer Present Regionally restricted 2C Expression in regions of differentiating neurons in marginal zones of diencephalon and telencephalic vesicles.
TS19: telencephalon marginal layer Present Regionally restricted 2C Expression in regions of differentiating neurons in marginal zones of diencephalon and telencephalic vesicles.
TS19: Rathke's pouch Present 2C
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon marginal layer Present Regionally restricted 3A Expression in neurons that just began differentiation in marginal zones of diencephalon.
TS17: trigeminal ganglion Present Regionally restricted 3A
Specimen E10.5 not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present
Specimen 4A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain marginal layer Present Uniform 4A Unifrom expression in thick layer of post-mitotic neurons in marginal zones of midbrain and hindbrain.
TS19: midbrain marginal layer Present Uniform 4A Unifrom expression in thick layer of post-mitotic neurons in marginal zones of midbrain and hindbrain.
Specimen 4C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain marginal layer Present Regionally restricted 4C Expression in marginal zone of brainstem.
TS19: dorsal root ganglion Strong 4C
TS19: heart atrium Present 4C
TS19: heart ventricle Weak 4C Less intense expression in ventricles of heart.
Specimen 5B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain marginal layer Present Regionally restricted 5B Expression limited to marginal zone of hindbrain.
Specimen 5D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain marginal layer Present Regionally restricted 5D Expression limited to marginal zone of hindbrain.
Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: remnant of Rathke's pouch Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory