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Tg(Gad2-EGFP)30Gsz
Transgene Detail
Summary
Symbol: Tg(Gad2-EGFP)30Gsz
Name: transgene insertion 30, Gabor Szabo
MGI ID: MGI:5920019
Synonyms: GAD65 3e/gfp5.5#30, GAD65_3e/gfp5.5 30, GAD65-EGFP, GAD65-GFP
Transgene: Tg(Gad2-EGFP)30Gsz  Location: unknown  
Alliance: Tg(Gad2-EGFP)30Gsz page
Transgene
origin
Strain of Origin:  (CBA x C57BL/6J)F2
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation details: A genomic clone, containing a 5.5 kb upstream region and the first six exons of the mouse GAD2 (GAD65) gene, was modified to express the eGFP marker gene without its own translation start site. The EGFP cDNA was fused in frame to the third exon of the Gad2 (GAD65) gene. Expression of eGFP occurs almost exclusively in the GABAergic neurons in many brain regions, including the neocortex and hippocampus. Line 30 was created. (J:245841)
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:245841 Brager DH, et al., Regulation of exocytosis from single visualized GABAergic boutons in hippocampal slices. J Neurosci. 2003 Nov 19;23(33):10475-86
All:  47 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory