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Tg(CAG-cat,-Prkaa1)#Mhzo
Transgene Detail
Summary
Symbol: Tg(CAG-cat,-Prkaa1)#Mhzo
Name: transgene insertion, Ming-Hui Zou
MGI ID: MGI:5919974
Transgene: Tg(CAG-cat,-Prkaa1)#Mhzo  Location: unknown  
Alliance: Tg(CAG-cat,-Prkaa1)#Mhzo page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-cat,-Prkaa1)#Mhzo expresses 1 gene
 
Mutation detailsThe construct consists of the mouse gene inserted downstream of the CAG promoter and a loxP site flanked chloramphenicol acetyltransferace gene. The cat gene blocks the expression of the mouse gene. The mouse gene is expressed only after removal of the cat gene through cre-mediated recombination. The pound # sign is used in the symbol because no line was specified. (J:242770)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:242770 Zhang M, et al., AMP-activated protein kinase alpha1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation. J Biol Chem. 2017 May 12;292(19):7888-7903
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory