Tg(Gcg-Venus)mGLU-V23-124Fmgb
Transgene Detail
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| Symbol: |
Tg(Gcg-Venus)mGLU-V23-124Fmgb |
| Name: |
transgene insertion mGLU-V23-124, Fiona M Gribble |
| MGI ID: |
MGI:5912113 |
| Transgene: |
Tg(Gcg-Venus)mGLU-V23-124Fmgb Location: unknown
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| Alliance: |
Tg(Gcg-Venus)mGLU-V23-124Fmgb page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The Venus YFP reporter gene was cloned into mouse BAC RP23-343C17, replacing the coding region of the glucagon gene (Gcg) from the start codon in exon 2 to the stop codon in exon 6. The experimental procedures introduced a nucleotide substitution in the non-coding sequence of exon 2, where it was deemed not to interfere with the expression. The final construct was injected into the pronuclei of fertilized (C57BL/6 x CBA)F1 eggs. The estimated copy number of this transgene is 12.
(J:238690)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:238690 Reimann F, et al., Glucose sensing in L cells: a primary cell study. Cell Metab. 2008 Dec;8(6):532-9 |
| All: |
3 reference(s) |
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Analysis Tools
