About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:173393 Chung SH, et al., Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum. Neural Dev. 2011;6:25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5912037
Gene symbol: Nrgn
Gene name: neurogranin
Antibody: anti-NG
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was 4% paraformaldehyde/0.02% glutaraldehyde with a post-fix in 4% paraformaldehyde.
Results
Specimen 7A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule IX Present Single cells 7A , 7C Expression is in Golgi interneurons.
Specimen 7B: postnatal adult; Plagl1tm1Jour/Plagl1+ (more )
Note: Zac1+m/- heterozygotes are effectively Zac1 null mutants due to maternal imprinting of the Plagl1 locus.
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule IX Present Single cells 7B , 7D The number of expressing cells is reduced in this mutant (approximately 63% of that of wild-type).
Specimen 7E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule V Present Single cells 7E Expression is in Golgi interneurons.
TS28: cerebellum vermis lobule VI Present Single cells 7E Expression is in Golgi interneurons.
Specimen 7F: postnatal adult; Plagl1tm1Jour/Plagl1+ (more )
Note: Zac1+m/- heterozygotes are effectively Zac1 null mutants due to maternal imprinting of the Plagl1 locus.
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule V Present Single cells 7F Expression in this mutant is the same as in wild-type.
TS28: cerebellum vermis lobule VI Present Single cells 7F Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory