Tg(Ucp1-icre)#Jcbr
Transgene Detail
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| Symbol: |
Tg(Ucp1-icre)#Jcbr |
| Name: |
transgene insertion, Jens C Bruning |
| MGI ID: |
MGI:5911694 |
| Synonyms: |
Ucp1-Cre |
| Transgene: |
Tg(Ucp1-icre)#Jcbr Location: unknown
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| Alliance: |
Tg(Ucp1-icre)#Jcbr page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Ucp1-icre)#Jcbr expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Ucp1 (MGI:98894) |
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Mutation details: A cassette containing iCre recombinase, an artificial intron, a bovine growth hormone polyadenylation signal, and an ampicillin-resistance gene flanked by FRT sites (Flpe
recombinase recognition sequence) was recombined into the first exon of the Ucp1 gene of a bacterial artificial chromosome (BAC RP23-248O16). An FRT site flanked ampicilin-resistance gene and a loxP site were removed. DNA from the modified BAC clone was used as the source for the transgene, which was microinjected into the pronucleus of C57BL/6N fertilized eggs. One of four founders expressed the transgene, and was selected for analysis. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:215519)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Ucp1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:215519 Turpin SM, et al., Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metab. 2014 Oct 7;20(4):678-86 |
| All: |
2 reference(s) |
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Analysis Tools
