Dmbx1tm2(cre/ERT2)Miki
Targeted Allele Detail
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Symbol: |
Dmbx1tm2(cre/ERT2)Miki |
Name: |
diencephalon/mesencephalon homeobox 1; targeted mutation 2, Takashi Miki |
MGI ID: |
MGI:5911627 |
Synonyms: |
Dmbx1creERT2 |
Gene: |
Dmbx1 Location: Chr4:115772316-115797123 bp, - strand Genetic Position: Chr4, 53.07 cM
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Alliance: |
Dmbx1tm2(cre/ERT2)Miki page
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Germline Transmission: |
Earliest citation of germline transmission:
J:233637
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intragenic deletion
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Dmbx1tm2(cre/ERT2)Miki expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A vector coding for a splice acceptor, IRES, and Cre/ERT2 fusion protein and neo selection cassette replaced a portion of exon 2 immidiately after ATG translation initiation site of Dmbx1 gene via homologous recombination.
(J:233637)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Dmbx1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dmbx1 Mutation: |
20 strains or lines available
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Original: |
J:233637 Hirono S, et al., Importance of Adult Dmbx1 in Long-Lasting Orexigenic Effect of Agouti-Related Peptide. Endocrinology. 2016 Jan;157(1):245-57 |
All: |
1 reference(s) |
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