Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tmprss2tm1.1(cre/ERT2)Ychen
Name:	transmembrane protease, serine 2; targeted mutation 1.1, Yu Chen
MGI ID:	MGI:5911389
Synonyms:	Tmprss2-CreERT2
Gene:	Tmprss2  Location: Chr16:97365882-97412395 bp, - strand  Genetic Position: Chr16, 57.53 cM, cytoband C2
Alliance:	Tmprss2tm1.1(cre/ERT2)Ychen page

Germline Transmission:	Earliest citation of germline transmission: J:243736
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6J

Allele Type:    Targeted (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutations:    Insertion, Intragenic deletion   Tmprss2tm1.1(cre/ERT2)Ychen expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tmprss2 (MGI:1354381)   Mutation details: The targeting construct replaced exon 2 with an FRT-flanked neomycin resistance cassette, an inducible cre recombinase gene (cre/ERT2), and IRES-nlsGFP. Flp-mediated recombination removed the selection cassette. (J:243736)

Activity:	Tissue activity of this recombinase allele
Driver:	Tmprss2 (mouse) Summary of all recombinase alleles driven by Tmprss2. Comparative matrix view of recombinase activities Alliance mouse Tmprss2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmprss2 Mutation:	46 strains or lines available

Original:	J:243736 Gao D, et al., A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon. PLoS One. 2016;11(8):e0161084
All:	6 reference(s)