Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Tff1-cre/ERT2)#Ern
Name:	transgene insertion, Matthias Ernst
MGI ID:	MGI:5911315
Transgene:	Tg(Tff1-cre/ERT2)#Ern  Location: unknown
Alliance:	Tg(Tff1-cre/ERT2)#Ern page

Strain of Origin:

(C57BL/6 x CBA)F1

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Tff1-cre/ERT2)#Ern expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Tff1   Mutation details: BAC recombineering was used to generate a vector with the CreERT2 open reading frame with a polyadenylation signal inserted immediately downstream of the endogenous ATG initiation codon in the Tff1 locus. The purified construct was used for pronuclear injection to generate transgenic lines. Line numbers were not indicated. (J:231629)

Activity:	Tissue activity of this recombinase allele
Driver:	Tff1 (species not specified) Summary of all recombinase alleles driven by Tff1.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:231629 Thiem S, et al., Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model. Cancer Res. 2016 Apr 15;76(8):2277-87
All:	6 reference(s)