Tg(ACTB-Wld)4836Cole
Transgene Detail
|
|
| Symbol: |
Tg(ACTB-Wld)4836Cole |
| Name: |
transgene insertion 4836, Michael Coleman |
| MGI ID: |
MGI:5911105 |
| Transgene: |
Tg(ACTB-Wld)4836Cole Location: unknown
|
| Alliance: |
Tg(ACTB-Wld)4836Cole page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(ACTB-Wld)4836Cole expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Wld (MGI:98952) |
expresses Wlds fusion gene |
|
| |
|
Mutation details: A construct consisting of the human beta actin promoter followed by the cDNA for Wlds that is an in-frame fusion of exon 1 and 2 of Ube4b to exon 2 onwards of Nmnat1, was injected into the pronuclei of fertilized (C57BL/6 x CBA)F1 eggs that do not express Wlds. Expression level of this transgene is similar to that of Wlds in the C57Bl/6Ola strain.
(J:72936)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:72936 Mack TG, et al., Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nat Neurosci. 2001 Dec;4(12):1199-206 |
| All: |
1 reference(s) |
|
Analysis Tools
